Table 1.
Selected Baseline Characteristics of Per Protocol Participants by Group
| Characteristics | Gentamicin + Azithromycin (n = 202) | Gemifloxacin + Azithromycin (n = 199) |
|---|---|---|
| Age, y, median (IQR) | 26 (22–35) | 29 (22–36) |
| Sex and sex of sex partner | ||
| Women | 19 (9.4) | 21 (10.6) |
| MSM | 67 (33.2) | 77 (38.7) |
| MSW | 116 (57.4) | 101 (50.8) |
| Self-identified race/ethnicity | ||
| Asian/Hawaiian/Pacific Islander | 6 (3.0) | 5 (2.5) |
| Non-Hispanic black | 126 (62.4) | 103 (51.8) |
| Non-Hispanic white | 44 (21.8) | 45 (22.6) |
| Hispanic or Latino | 18 (8.9) | 28 (14.1) |
| Multiracial | 7 (3.5) | 12 (6.0) |
| Other | 1 (0.5) | 6 (3.0) |
| Enrolling site | ||
| Baltimore, Maryland | 1 (0.5) | 2 (1.0) |
| Birmingham, Alabama | 60 (29.7) | 53 (26.6) |
| Los Angeles, California | 4 (2.0) | 5 (2.5) |
| Pittsburgh, Pennsylvania | 40 (19.8) | 38 (19.1) |
| San Francisco, California | 97 (48.0) | 101 (50.8) |
| Previous STD (by participant self-report) | ||
| Gonorrhea | 85 (42.1) | 92 (46.2) |
| Chlamydia | 82 (40.6) | 85 (42.7) |
| HIV infection (by participant self-report) | ||
| Positive | 19 (9.4) | 16 (8.0) |
| Negative | 159 (78.7) | 163 (81.9) |
| Unknown | 24 (11.9) | 20 (10.1) |
| Symptoms | ||
| Penile or vaginal discharge | 182 (90.1) | 179 (89.8) |
| Dysuria | 153 (75.7) | 138 (69.3) |
| Dyspareunia | 22 (10.9) | 23 (11.6) |
| Anal pain or discharge | 4 (2.0) | 2 (1.0) |
| Sore throat | 9 (4.5) | 14 (7.0) |
| Exam findings | ||
| Penile discharge (among men) | 177 (96.7) | 169 (94.9) |
| Vaginal discharge (among women) | 17 (89.5) | 20 (95.2) |
| Anal tenderness or discharge | 0 (0.0) | 1 (0.5) |
| Pharyngeal erythema or exudate | 6 (3.0) | 11 (5.5) |
| Additional infections diagnosed | ||
| Bacterial vaginosis (among women) | 9 (47.4) | 10 (47.6) |
| Chlamydiaa | 51 (25.9) | 47 (23.7) |
| Pharyngeal gonorrhea | 10 (5.0) | 15 (7.5) |
| Rectal gonorrhea | 1 (0.5) | 5 (2.5) |
Data are presented as No. (%) unless otherwise indicated.
Abbreviations: HIV, human immunodeficiency virus; IQR, interquartile range; MSM, men who have sex with men; MSW, men who report sex exclusively with women; STD, sexually transmitted disease.
a Denominators of 197 (gentamicin/azithromycin) and 198 (gemifloxacin/azithromycin) due to inevaluable results.