Table 3.

Antimicrobial Susceptibility of Pretreatment Neisseria gonorrhoeae Isolates Collected From Participants in the Per Protocol Analysis (n = 421)^a

Antimicrobial	MIC50, µg/mL	MIC90, µg/mL	Range, µg/mL	Percentage at or Above MIC Breakpoint	MIC Breakpoint for Resistance or Elevated MICs, µg/mL
Azithromycin	0.25	0.5	0.03–16	0.5	≥2.0
Cefixime	0.015	0.06	0.001–1.0	1.4	≥0.25
Ceftriaxone	0.008	0.03	0.001–0.125	1.2	≥0.125
Ciprofloxacin	0.004	8.0	0.002–32.0	24.5	≥1.0
Gemifloxacin	0.004	2	0.001–8.0	17.1	≥1.0
Gentamicin	4	8	0.002–16	0	≥32.0
Penicillin	0.5	4	0.004–64	23.0	≥2.0
Tetracycline	0.5	16	0.03–>32	24.2	≥2.0

Abbreviations: MIC, minimum inhibitory concentration; MIC₅₀, minimum inhibitory concentration required to inhibit growth of 50% of organisms; MIC₉₀, minimum inhibitory concentration required to inhibit growth of 90% of organisms.

^a Three hundred ninety-six participants provided a total of 421 isolates (participants with genital and extragenital infections may have contributed >1 pretreatment isolate).