FIG. 3.

Dose- and exposure period-dependent differential gene expression in male Long Evans, Fischer 344, and Sprague Dawley rats. Heat map visualization of transcript profiles show differential expression in perinatal and postnatal conditions both within and across strains. The vertical bars adjacent to the heat maps indicate the genes that show significant changes for each of the two lead dose levels studied. Up- and downregulated gene expression is represented by red and green, respectively in the heat maps. Fold-change calibration bar (−1 to 1) appears at the bottom of the figure.