FIG. 10.

Cardiomyocyte overexpression of AHR2 and heart malformation. Embryos were exposed to vehicle or TCDD just after fertilization or injected with cmlc2:AHR2–2AtRFP or cmlc2:AHR2^−dbd-2AtRFP expression constructs. (A) Brightfield and fluorescent images showing lateral views with anterior to the left. The arrow indicates position of the heart and asterisks indicate autofluorescence. (B) The incidence of heart malformation following each treatment: white bar, vehicle (n = 5); black bar, TCDD (n = 5); light gray bar, AHR^−dbd (n = 18); and dark gray bar, AHR2 (n = 42). Error bar represents standard error of the mean.