FIG. 2.
Cos7 Transactivation assay. Plasmids expressing AHR2, AHR2dbd, caAHR, caAHRdbd, or GFP were transfected into Cos7 cells along with an ARNT1c expression vector and the AHRE-driven luciferase reporter pGudLuc as detailed in the Materials and Methods. Cells were treated with either TCDD (black bars) or DMSO (white bars). The average luciferase activity is shown relative to a transfection control. Error bars represent standard error of the mean. Lowercase letters indicate a significant difference between samples with other letters (P < 0.05), n = 3.