FIG. 4.

Cardiomyocyte expression of caAHR causes heart malformation. Immediately after fertilization, embryos were treated with DMSO, or TCDD in water, or they were injected with cmlc2:caAHR^−dbd-2AtRFP or cmlc2:caAHR-2AtRFP DNA as described in the Materials and Methods. Brightfield (left) and RFP fluorescence (right) images at 96 hpf of representative samples. Specimens are positioned such that the heart is at center with the eye at the left edge and the yolk sac at right. Ventricle (V) and atrium (A) are labeled. The arrow indicates the ventricle, asterisks indicate regions of autofluorescence.