Cardiomyocyte expression of caAHR causes circulation failure. Immediately after fertilization, embryos were treated with DMSO, or TCDD in water, or they were injected with cmlc2:caAHR−dbd-2AtRFP or cmlc2:caAHR-2AtRFP DNA as described in the Materials and Methods. Blood flow was measured at 96 hpf as the number of red blood cells perfusing an intersegmental artery in the posterior trunk within 10 s. White bar, DMSO; black bar, TCDD; light gray bar, caAHR−dbd; and dark gray bar, caAHR. Lowercase letters indicate a significant difference between samples with other letters (P < 0.05), n = 5 for each treatment. Error bars represent standard error of the mean.