TABLE 1. Effect of In Utero TCDD Exposure on Abundance and Localization of RNA from Wnt Genes in Mouse UGS at E16.5a.
aAt least three litter-independent UGSs per treatment group were used to determine RNA abundance and localization for each gene. Corn oil (vehicle) or TCDD (5 μg/kg, po) was administered to pregnant dams on E15.5. A horizontal arrow denotes that RNA was detected in the indicated tissue compartment and that there was no detectable difference in RNA abundance or localization between vehicle- and TCDD-exposed UGSs at E16.5. Upward-pointing arrows indicate that TCDD increased transcript abundance compared with vehicle-exposed control UGSs. No arrow indicates that transcript was not detected.
bBasal epithelium = epithelial cells bordering mesenchyme.
cIntermediate epithelium = epithelial cells that do not border mesenchyme or lumen.
dVentral lamina propria = mesenchyme immediately adjacent to the epithelium in the ventral UGS.