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Non-oxidative and oxidative ribose synthesis phase plane (output–output analysis). Under high oxygen exposure, lipofibroblasts (•) from immature lung differentiate into myofibroblasts (
). The metabolic phenotype change is indicated by the increased use of the non-oxidative pathways for ribose synthesis and its restriction on the production of reducing equivalents from the oxidative pathway. Data are adapted from article of Boros et al. (2002c).
