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Increased expression of IFNB transcripts in human monocyte-derived macrophages in response to cytosolic poly(I:C) response is not dependent on the toll-like receptor pathway
HMBS is hydroxymethylbilane synthase.
| Treatment | siRNA | IFNB mRNA copies/HMBS |
|---|---|---|
| Transfected poly(I:C) | Scrambled control | 341.1 ± 49.5a |
| Transfected poly(I:C) | MyD88 | 2083.7 ± 101.1 |
| Transfected poly(I:C) | TRIF (TICAM-1) | 1370.2 ± 160.8 |
a p < 0.01 (ANOVA, n = 3).
