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. 2014 Oct 24;289(51):35351–35362. doi: 10.1074/jbc.M114.593376

FIGURE 7.

FIGURE 7.

Mapping of catalytic residues in GBA2. a, schematic depicting GBA2 putative catalytic residues (shades of gray), with possible acid/base D667 (left, gray) and nucleophile Glu-527 (black). b, sequence alignment of GBA2 homologues of various species, with highly conserved aspartic (D) and glutamic acids (E).