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I-BET151 attenuates Gli1 expression. A, a model of the HH signaling pathway, showing pivotal positive (green) and negative (red) regulators. B, Light2 cells stimulated with SAG (100 nm) were treated with the indicated doses of I-BET151, and the expression levels of various HH signaling components were determined. Error bars represent the S.E. of three independent experiments.
