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. 2014 Nov 4;289(51):35503–35516. doi: 10.1074/jbc.M114.590687

FIGURE 5.

FIGURE 5.

Hes3 regulates responses to challenge by glucose/KCl in MIN6 cell cultures. A–C, insulin content, released insulin, and stimulation index measurements by ELISA (stimulation index is expressed as % of control siRNA) following transfection with either a control siRNA or Hes3 siRNA show that opposing Hes3 expression reduces the responsiveness to stimulation in MIN6 cells cultured in DC (n = 3; errors bars represent S.E. R, resting state; S, stimulated state).