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. Author manuscript; available in PMC: 2014 Dec 19.
Published in final edited form as: JAMA Intern Med. 2014 Sep;174(9):1514–1516. doi: 10.1001/jamainternmed.2014.3450

Table 2.

Impact of Cognitive Status on Receipt of Incident Pacemaker

Cognitive Status Adjusted OR (95% CI)a
Cognitive status the visit before assessed for incident pacemaker
    MCIb 1.2 (0.9-1.7)
    Dementiac 1.6 (1.1-2.5)
    No cognitive impairmentd 1 [Reference]
CDR the visit before assessed for incident pacemaker
    0.5, MCI 1.5 (1.1-2.1)
    1, Mild dementia 1.6 (1.0-2.5)
    2, Moderate dementia 1.5 (0.7-3.1)
    3, Severe impairment 2.9 (1.2-7.4)
    0, No cognitive impairment 1 [Reference]
Cognitive status the visit before and the visit assessed for incident pacemaker
    Stable MCI at both visits 1.1 (0.7-1.7)
    Stable dementia at both visits 1.8 (1.2-2.8)
    No cognitive impairment with decline to MCI or dementia 1.3 (0.8-2.3)
    MCI with decline to dementia 1.7 (1.0-3.1)
    Dementia or MCI with an improvement to MCI or no impairment 1.2 (0.6-2.3)
    Stable; no cognitive impairment at both visits 1 [Reference]

Abbreviations: CDR, clinical dementia rating; MCI, mild cognitive impairment; OR, odds ratio.

a

Analyses were adjusted for sex; age; race; pacemakers per1000 Medicare beneficiaries in the Alzheimer Disease Centers hospital referral region; and time-varying variables for functional status, cardiac comorbidity status, hypertension, and Hachinski Ischemic Score.

b

Unadjusted rates of incident pacemaker device, 4.7 per 1000 person-years.

c

Unadjusted rates of incident pacemaker device, 6.5 per 1000 person-years.

d

Unadjusted rates ofincident pacemaker device, 4.0 per 1000 person-years.