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. 2014 Dec 6;13:184. doi: 10.1186/1476-511X-13-184

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© Gomes et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Kidney weight/body weight ratio (A), glomerular tuff area (B), glomerulosclerosis (C) in diabetic mice treated with quercetin (DQ) compared to diabetic mice administered with vehicle (DV) and non-diabetic (ND) mice. The mean value of 30 individual glomeruli areas from each kidney were used to calculate the glomerular tuff area and glomerulosclerosis. Micrographs (D) are representative glomerular sections (magnification of 400x) stained with Masson trichrome to identify sclerosis (blue) in each glomerulus. Values are means ± SEM for n = 6–8 mice per group. *p < 0.05 vs. ND, ^# p < 0.05 vs. DV.