Figure 1.

Diagram illustrating the study protocol. Maximum effort voluntary contractions (MVC) of the quadriceps were performed prior to the first measurements of the dependent variables. After a 5-minute rest period, transcranial magnetic stimulation was used to measure the dependent variables at baseline 1 (B1), 10 minutes later at baseline 2 (B2) and then immediately after experimental knee joint infusion (P1). At each measurement interval the dependent variables were measured with the quadriceps at rest (resting condition) and then during a quadriceps contraction at 10% of maximum voluntary contraction (active condition).