Table 1.
Localization of inhibin subunit antibody immunoreactivity in human control (Ctrl) and idiopathic pulmonary fibrosis (IPF) lung
| Patient | Inhibin ß A | Inhibin ß B | Follistatin | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Localization | (H)AEC | BE | MΦ | (H)AEC | BE | MΦ | (H)AEC | BE | MΦ |
| Ctrl1 | - | - | ++ | - | - | - | - | +++ | ++ |
| Ctrl2 | - | + | + | - | + | + | - | - | ++ |
| Ctrl3 | - | + | + | - | + | + | - | +++ | +++ |
| Ctrl4 | - | - | - | - | + | + | - | ++ | ++ |
| Ctrl5 | - | - | - | - | - | - | - | ++ | ++ |
| IPF/UIP1 | ++ | ++ | ++ | + | + | - | +++ | +++ | +++ |
| IPF/UIP2 | +++ | ++ | +++ | + | + | - | ++ | ++ | ++ |
| IPF/UIP3 | - | - | - | - | + | - | +++ | +++ | +++ |
| IPF/UIP4 | +++ | +++ | +++ | + | - | - | ++ | ++ | +++ |
| IPF/UIP5 | ++ | ++ | ++ | + | ++ | - | +++ | +++ | +++ |
The histopathological finding of IPF is usual interstitial pneumonia (UIP). (H)AEC, (hyperplastic) alveolar epithelial cells; BE, bronchial epithelial cells; MΦ, macrophages.