Table 1.
Concentration dependent cytotoxic potential of crude methanolic extracts of T. stocksianum and its sub-fractions against Brine shrimps nauplii
| Samples/Drug | Conc 10 μg/ml | Conc 100 μ/ml | Conc 1000 μ/ml | LC 50μ/ml |
|---|---|---|---|---|
| Crude saponins | 55.555 ± 1.112% | 63.332 ± 3.337% | 94.444 ± 2.943 | < 10 |
| Methanolic extract | 18.888 ± 5.886% | 35.555 ± 2.943% | 58.887 ± 2.944% | 620 |
| n- hexane fraction | 37.777 ± 2.943% | 42.221 ± 2.943% | 67.777 ± 2.224% | 80 |
| Chloroform fraction | 42.221 ± 2.943% | 59.999 ± 1.926% | 71.110 ± 2.943% | 55 |
| Ethyl acetate fraction | 16.666 ± 1.926% | 28.888 ± 1.112% | 54.444 ± 2.943% | 860 |
| Aqueous fraction | 12.221 ± 2.943% | 27.777 ± 2.943% | 49.998 ± 1.926% | 1000 |
Conc; concentration. Values are expressed as the mean ± SEM of three independent observations. Standard drug; Etoposide LD50 = 9.8 μg/ml.