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. 2014 Dec 2;9:261. doi: 10.1186/s13014-014-0261-z

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© Gurtner et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect on tumour growth time. Time to reach 2-fold or 5-fold the starting volume for A7, A431, FaDu, UT-SCC-14 and UT-SCC-15 xenografts receiving either carrier (○) or BIBW 2992 (◊) or the combined treatment of 15f/15d + carrier (closed circle symbol) or 15f/15d + BIBW 2992 (closed diamond symbol). Symbols represent median and bars 95% confidence intervals. p-value in comparison to control groups *significant difference (comparison between BIBW 2992 vs. carrier or combined IR + BIBW 2992 vs. IR + carrier).