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. 1973 Oct;70(10):2983–2987. doi: 10.1073/pnas.70.10.2983

In Vitro Production of Mouse Mammary Tumor Virus in a Mouse Mammary Tumor Ascites Line

Jafa Keydar *, Zvee Gilead *, Jacob R Hartman *, Yehuda Ben-Shaul †
PMCID: PMC427152  PMID: 4126729

Abstract

An ascites line derived from a spontaneous mouse mammary carcinoma produces, on explantation and cultivation in vitro, large amounts of oncornavirus particles. The biochemical, biophysical, and electron microscopic characteristics of the virions are described. Molecular hybridization and immunological methods identify these virions as mouse mammary tumor virus.

Keywords: RNA-directed DNA polymerase, 70S RNA, viral antigens, DNA-RNA hybridization

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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