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. 2014 Dec 19;8:147. doi: 10.3389/fncir.2014.00147

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Copyright © 2014 Hsieh, Ulrich, Issa, Wan and Papazian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Direct electrical stimulation of inferior olive increases occurrence of complex spike-like events. (A) Upper: The inferior olive was stimulated using a theta pipette (see Figure 1B) at the time indicated by the red dashed line. Shown is a representative recording of Purkinje cell activity obtained at 5 dpf. Lower: The portion of the upper trace marked by a bar is shown on an expanded time scale. Red dots indicate complex spikes. (B) Peristimulus raster plot shows the occurrence of complex spikes before and after stimulation of the inferior olive at time 0 (red dashed line). Results were obtained from nine Purkinje cells from four animals at 5 dpf. The trace shown in panel (A) corresponds to cell #3.