Table 3.
Clinical characteristics and treatment outcomes*
| Patients still living (n = 101) | Patients deceased (n = 15) | |
|---|---|---|
| Age, mean ± SD years | 40.9 ± 17.7 | 45.8 ± 24.9 |
| Male sex, no. (%) | 19 (18.8) | 9 (60.0)† |
| Physical findings | ||
| Fever, no./total no. (%)‡ | 85/99 (85.9) | 14/15 (93.3) |
| Lymphadenopathy, no./total no. (%) | 27/69 (39.1) | 5/9 (55.6) |
| Hepatomegaly, no./total no. (%) | 20/55 (36.4) | 8/12 (66.7) |
| Splenomegaly, no./total no. (%) | 34/77 (44.2) | 6/11 (54.5) |
| Laboratory findings | ||
| WBC count, mean ± SD ×109/liter | 3.7 ± 5 | 7.2 ± 11.8 |
| Hgb, mean ± SD gm/dl | 9 ± 2 | 8.8 ± 2.3 |
| Platelet count, mean ± SD ×109/liter | 130.6 ± 131.7 | 83.3 ± 104 |
| Coagulopathy, no./total no. (%)§ | 33/69 (47.8) | 7/10 (70) |
| AST, mean ± SD IU/liter | 224.8 ± 448.2 | 571.2 ± 1034 |
| ALT, mean ± SD IU/liter | 164.1 ± 318.9 | 302.7 ± 514.9 |
| LDH, mean ± SD IU/liter | 1,196 ± 1,571 | 1,714 ± 1,784 |
| CRP, mean ± SD mg/dl | 7.5 ± 10.4 | 9.3 ± 8.1 |
| Ferritin, mean ± SD μg/liter | 12,963 ± 27,982 | 32,133 ± 66,866 |
*
WBC = white blood cell; Hgb = hemoglobin; AST = aspartate aminotransferase; ALT = alanine aminotransferase; LDH = lactate dehydrogenase; CRP = C-reactive protein.
†
P < 0.01 versus patients still living.
‡
Body temperature ≥37.5°C.
§
Hypofibrinogenemia, increased fibrinogen degradation products, or prolonged prothrombin time or activated partial thromboplastin time.