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. 2014 Oct 9;6(6):1759091414554946. doi: 10.1177/1759091414554946

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© The Author(s) 2014

This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (http://www.uk.sagepub.com/aboutus/openaccess.htm).

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Figure 4. — Consumption of Sutherlandia and elderberry diets attenuates activation of microglial cells but not astrocytes in the striatal regions after transient global cerebral ischemia.

(a) Graphical illustration of the five representative areas selected bilaterally for captured intensity analysis. (b) Representative fluorescent microscopic images of Iba-1 immunoreactivity among all groups; Scale bar = 100 µm. Inset in Sham/CD panel shows representative cells of the ramified resting microglia, while inset in Isch/CD panel shows the amoeboid form of activated microglia; Scale bar = 25 µm. Quantitation of the average fluorescent intensity for Iba1 (c) and GFAP (d) immunoreactivity from five areas in the striatum (n = 5 for all groups). Data are expressed as means ± SEM. Statistical significance is denoted with *p < .05, ***p < .001 (compared with Sham/CD); and ^^^p < .001 (compared with Isch/CD) by one-way ANOVA followed by Bonferroni’s posttest.