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. Author manuscript; available in PMC: 2014 Dec 19.
Published in final edited form as: Toxicol Pathol. 2011 Oct 21;40(1):5–17. doi: 10.1177/0192623311425062

Table 3.

Incidences (%)a of the prostate lesions identified as most common in each lobe of the prostates of TRAMP mice.

Lesion Prostate lobe
Ventral Lateral Dorsal Anterior
Normal 4.8 0b 0b 59.5
Low-grade PIN 9.5 0b 0b 0b
Moderate-grade PIN 14.3 14.3 2.4 0b
High-grade PIN 2.4 19.0 45.2 2.4
Phyllodes-like 0c 0c 0b 0b
Well-differentiated adenocarcinoma 2.4 2.4 0b 0c
Moderately differentiated adenocarcinoma 2.4 0b 0c 0c
Poorly differentiated carcinoma 64.3 64.3 52.4 38.1

PIN = prostatic intraepithelial neoplasia; TRAMP = transgenic adenocarcinoma of the mouse prostate.

a

Incidence expressed as a percentage of a total of 42 mice.

b

Lesions of this type were observed but did not represent the most common lesion in this lobe in any of the mice.

c

No lesions of this type were observed in this lobe.