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. Author manuscript; available in PMC: 2014 Dec 19.
Published in final edited form as: J Neurosci Res. 2008 Sep;86(12):2763–2773. doi: 10.1002/jnr.21721

Fig. 3. Tau and hsc70 show specific, high-affinity binding measured by surface plasmon resonance (SPR).

Fig. 3

A range of 3R or 4R tau analyte concentrations was injected over a test surface containing immobilized bovine hsc70. The relative changes in SPR signal, as obtained by subtracting the signal of a control dextran surface from that of the hsc70 test surface, are shown. Analyte injection lasted 90 sec (association phase) and the dissociation phase, starting at time = 90 sec, was monitored for at least 180 sec. Sensorgrams shown are from a single representative experiment; however, multiple injections with a wider range of tau concentrations were used calculate the values shown in Table I