Figure 6. The status of genomic and transcriptomic alterations of representative genes, detected by WGS and RNA-Seq of 22 HBV-related HCCs.

The list of genes were extracted by (1) significantly mutated genes in WGS analysis, (2) having no less than 3 mutations (point mutations or indels in coding regions, or GMTAs), (3) having no less than 2 GMTAs and registered in cancer gene census [17]. (4) involved in WNT signaling pathway, (5) TERT or MLL4.