Table 2. Time-change profile of plasma liraglutide concentration following subcutaneous administration of liraglutide in diabetic patients with ESRD on the days of on-hemodialysis and off-hemodialysis.
Type of Hemodialysis | Off-hemodialysis (day 2) | On-hemodialysis (day 3) | Mean ratio |
p mol (Mean±SE) | p mol (Mean±SE) | (95% Confidence interval) | |
2 hr | 15479±4413 | 19224±5280 | 1.25 (0.96–1.62) |
6 hr | 18663±5218 | 21185±6188 | 1.12 (0.86–1.45) |
9 hr | 19568±4930 | 21582±6260 | 1.08 (0.83–1.40) |
12 hr | 19392±5053 | 20483±5289 | 1.06 (0.82–1.38) |
15 hr | 18441±5206 | 20939±6674 | 1.10 (0.84–1.42) |
24 hr | 14486±4902 | 16670±6107 | 1.14 (0.88–1.49) |
n = 10.