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. Author manuscript; available in PMC: 2014 Dec 19.
Published in final edited form as: Q Rev Biophys. 2012 May 9;45(3):301–343. doi: 10.1017/S0033583512000066

Fig. 1.

Fig. 1

The conformational variation in holo- and apo structures of beta-secretase 1 illustrates structural differences frequently seen across multiple crystal structures of the same protein.