Table 1.
CON | INS | |
---|---|---|
Maternal | ||
Glucose, mg/dL | 70.0 ± 3.3 | 72.6 ± 2.7 |
pH | 7.44 ± 0.01 | 7.46 ± 0.01 |
PaCO2, mm Hg | 34.6 ± 0.8 | 34.3 ± 0.6 |
Lactate, mmol/L | 0.66 ± 0.05 | 1.05 ± 0.16 |
PaO2, mm Hg | 90.2 ± 1.0 | 91 ± 2.2 |
Hemoglobin-SaO2 % | 96.3 ± 0.8 | 97.5 ± 0.5 |
O2 content, mmol/L | 5.9 ± 0.1 | 5.5 ± 0.2 |
Hct, % | 31.7 ± 0.8 | 28.9 ± 0.8a |
Fetal | ||
pH | 7.34 ± 0.00 | 7.34 ± 0.01 |
PaCO2, mm Hg | 51.8 ± 1.2 | 55.3 ± 0.9 |
Lactate, mmol/L | 2.0 ± 0.12 | 1.7 ± 0.11 |
Hct, % | 35.4 ± 1.0 | 35.0 ± 2.6 |
IGF-I, ng/mL | 116.6 ± 10.5 | 151.5 ± 12.6a |
Cortisol, ng/mL | 9.08 ± 1.13 | 9.38 ± 2.76 |
NE, pg/mL | 522 ± 106 | 1160 ± 438b |
Glucagon, pg/mL | 44.34 ± 26.91 | 42.84 ± 6.18 |
Abbreviations; Hct, hematocrit; IGF1, insulin like growth factor 1.
All values are mean ± SE and were obtained at the end of the chronic experimental infusion.
P < .05 CON (n = 9) vs INS (hyperinsulinemic, n = 8) by mixed models ANOVA.
P < .005 CON (n = 9) vs INS (hyperinsulinemic, n = 8) by mixed models ANOVA.