Table 1.
Treatment | Dose (μg/g BW) | Serum T4 | Serum T3 | TSHb mRNA | Body Weight | Lean Mass | Fat Mass | Liver Gene Expression | Food Intake | Total Cholesterol | Heart Weight | Energy Expenditure |
---|---|---|---|---|---|---|---|---|---|---|---|---|
T2 | 0.25 | ↓↓ | ↓ | ↓ | ↔ | ↔ | ↔ | ↔ | ↔ | ↔ | ND | ND |
T2 | 2.5 | ↓↓ | ↓↓ | ↓↓ | ↔ | ↑ | ↓ | ↑ | ↑ | ↓ | ↑ | ↑ |
T3 | 0.03 | ↓↓ | ↔ | ↓↓ | ↔ | ↑ | ↓ | ↑ | ↑ | ↓ | ND | ND |
BW, body weight; ND, not determined.