. Author manuscript; available in PMC: 2015 Nov 12.

Published in final edited form as: Cell Host Microbe. 2014 Nov 12;16(5):562–568. doi: 10.1016/j.chom.2014.10.009

Table 1. Gene.

Expression of HCV entry factors in humans and mice.

Gene		Tissue Expression		Liver expression		Protein Identity (%)
Human	Mouse	Human	Mouse	Human	Mouse	Protein Identity (%)
LDLR	Ldlr	Ubiquitous	Ubiquitous	+	+	79
SCARB1	Scarb1	Adrenal tissue, placenta, liver	Adrenal gland,ovary, liver	+	+	80
CD81	Cd81	Ubiquitous	Ubiquitous	+	+	92
CLDN1	Cldn1	Ubiquitous	Most abundantly skin,liver	+	+	91
CLDN6	Cldn6	Ubiquitous	Placenta	+	Low	87
CLDN9	Cldn9	Heart, muscle	Pituitary, pancreas	+	Low	97
OCLN	Ocln	Tight junctions	Tight junctions	+	+	89
EGFR	Egfr	Placenta, prostate, liver	Liver,cornea,osteobla st	+	+	88
EphA2	Epha2	Epithelial, endothelial cells	Epithelial, endothelial cells	+	+	92
TfR1	Tfr1	Early erythroid cells, liver	Bone marrow, placenta, liver	Low	Low	77
NPC1L1	Npc1l1	Ubiquitous	Small intestine	+	−	77
CIDEB	Cideb	Liver, small intestine	Liver, small intestine, kidney	+	+	86