Figure 3. IL-6 contributes to the development of colonic tumors but not to IL-17A expression.
CPC-APC mice heterozygous (+/−) or null (−/−) for the Il6 gene were sacrificed at 5 months of age and analyzed for tumor parameters (A, n=5) or IL-17A mRNA by Q-RT-PCR of mesenteric lymph node (MLN), normal colon (N) and tumor (T) tissues (B, n=9). Data represent averages ± S.E.M. * p < 0.05. See also Figure S5.