Table 2.
Group | Day 8 | Day 10 | Day 14 | Day 17 |
---|---|---|---|---|
1 | 138.5 ± 37.2 | 370.3 ± 184.0 | 1602.0 ± 845.2 | 4089.1 ± 1341.6a |
2 | 130.9 ± 39.2 | 282.3 ± 140.9 | 1320.8 ± 529.0 | 3149.8 ± 727.0 |
3 | 137.1 ± 37.0 | 308.0 ± 125.8 | 1207.2 ± 445.5 | 3081.9 ± 553.0 |
4 | 111.2 ± 36.6 | 294.9 ± 132.2 | 1095.2 ± 382.6 | 2901.9 ± 696.2 |
5 | 129.8 ± 39.2 | 275.4 ± 114.1 | 1306.7 ± 440.3 | 3194.5 ± 524.5 |
6 | 132.6 ± 43.3 | 264.9 ± 96.2 | 1181.5 ± 630.9 | 2742.2 ± 784.6 |
7 | 123.4 ± 44.0 | 261.1 ± 166.3 | 1057.5 ± 528.6 | 2473.0 ± 756.5 |
8 | 142.2 ± 44.3 | 225.9 ± 81.8 | 922.0 ± 303.7 | 2402.8 ± 562.6 |
P valueb | 0.71 | 0.24 | 0.05 | 0.0001 |
aMeans of the tumor volume for each group were not significantly different until day 14. ANOVA followed by SNK showed that on Day 14 the tumor volume of group 1 was significantly greater than that of groups 7 and 8 and that on Day 17, the tumor volume of Group 1 was significantly greater than that of all other groups. Group 1 had 20 mice, all other groups had 10 mice.
bP value from the ANOVA. The decreasing p value with time indicates that the differences between groups were increasing with time.
Tumor volume (mm3, mean ± SD).