TABLE 1.
Substrate | Km(app) (mM) | kcat(app) (s−1) | kcat/Km (M−1 s−1) |
---|---|---|---|
MSX | 576 ± 89 | 35 ± 2 | 6 × 104 |
MSO | 230 ± 56 | 31 ± 2 | 1 × 104 |
Acetyl-CoA | 156 ± 41 | 23 ± 1 | 2 × 104 |
The apparent kinetic parameters of the SeMddAWT protein were determined using a spectrophotometric assay described in Materials and Methods. The catalytic variant SeMddAE82Q was used as a negative control.