Skip to main content
. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Mol Cancer Res. 2014 Aug 4;12(12):1818–1828. doi: 10.1158/1541-7786.MCR-14-0167

Figure 5. RRP1B interacts with TRIM28 and HP1α at regions associated with H3K9me3 and decreased gene expression.

Figure 5

A, ChIP-reChIP with TRIM28 and RRP1B antibodies in MDA-MB-231 cells. *; P ≤ 0.05 compared to both IgG/TRIM28 and IgG/RRP1B controls. B, ChIP-reChIP with HP1α and RRP1B antibodies in MDA-MB-231 cells. *; P ≤ 0.05 compared to both IgG/HP1α and IgG/RRP1B controls. C, H3K9me3 ChIP-qPCR in MDA-MB-231 clonal isolates over-expressing RRP1B and control cell lines. D, H3K9me3 ChIP-qPCR in MDA-MB-231 cells transfected with either RRP1B siRNA or negative control siRNA. E, Venn diagram of unique and common H3K9me3-enriched regions identified by ChIP-seq in MDA-MB-231 clonal isolates over-expressing RRP1B and control cell lines.