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Magnetic Resonance Spectroscopy Changes after Tolvaptan showing an increase in Choline indicating reduction in astrocytic swelling
| Creatine ratio of metabolites | Right Parietal White Matter | Posterior Gray Matter | ||||
|---|---|---|---|---|---|---|
| Myoinositol | Choline | Glutamate+ Glutamine | Myoinositol | Choline | Glutamate+ Glutamine | |
| Pre-drug | 0.192±0.04 | 0.239±0.01 | 2.4±0.14 | 0.254±0.04 | 0.187±0.01 | 2.375±0.08 |
| After tolvaptan | 0.166±0.04 | 0.285±0.02 | 2.278±0.14 | 0.253±0.03 | 0.213±0.01 | 2.292±0.12 |
| P value | 0.53 | 0.014 | 0.53 | 0.62 | 0.009 | 0.61 |
