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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Gene. 2014 Nov 8;556(1):74–79. doi: 10.1016/j.gene.2014.11.009

Fig. 2. Expression of a mutational BRCA1 does not affect the Pol III gene.

Fig. 2

HCC 1937 cells were transfected with wt BRCA1 (lane 1–2) or a dominant negative mutant (mt) BRCA1 (lane 3–4) expression construct plus pArg Maxi gene as described in Fig. 1. RNase protection assay was carried out to determine the transcription levels of pArg Maxi gene (83nt). An example of autoradiogram is shown in (A). Quantification of 3 independent experiments of transfection with the constructs is showed (B). **: p<0.01.