Figure 3. Coding end structures in H2AX- and 53BP1-deficient cells.
Barplots indicating the percentage of pMX-DELCJ coding ends with top strand (5′) and bottom strand (3′) termini at specific nucleotide (NT) distances from the RAG DSB in LigIV−/−:DELCJ (128,122 sequences analyzed), LigIV−/−:H2AX−/−:DELCJ (72,923 sequences analyzed), and LigIV−/−:53BP1−/−:DELCJ (337,917 sequences analyzed) abl pre-B cells as described in Figure 2A. The LigIV−/−:DELCJ (BLig4CJ7), LigIV−/−:H2AX−/−:DELCJ (LH8CJ148), and LigIV−/−:53BP1−/−:DELCJ (B53BP1Lig4CJ6) abl pre-B cells were used for analysis. Also see related figures S4 and S6.