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. Author manuscript; available in PMC: 2015 Aug 1.

Published in final edited form as: Int J Obes (Lond). 2014 Jun 20;39(2):260–264. doi: 10.1038/ijo.2014.106

Table 1.

Baseline characteristics of study participants.

	Study 1 (n=6) (Study in the Isocaloric Fed state)	Study 2 (n=18) (Study in the weight reduced state after Bariatric surgery)	Study 3(n=8) (Study in the Fasting state with placebo / metreleptin in physiological doses)	Study 4 (n=15) (Study in the Fasting state with pharmacologic doses of metreleptin)	Study 5 (n=5) (Ex vivo treatment of omental fat with leptin)
Age (years)	22.3 (19-27)	52 (33-66)	23.3 (19-29)	21.9 (19-28)	48 (30-61)
Male	6 (100%)	8 (44.4%)	8 (100%)	10 (66.7%)	2 (40%)
Body mass index (kg/m²)	23.4 (20.6-25.1)	47.4 (37.1-74.6)	23.7 (20.6-25.2)	25.3 (20.2-34.6)	44.6 (40.0-50.4)
Type 2 diabetes mellitus	0 (0)	7 (38.9%)	0 (0)	N/A	2 (40%)
Type of surgery	N/A	Roux-en-Y: 7 (38.9%) Gastric banding: 11 (61.1%)	N/A	N/A	Roux-en-Y: 1 (20%) Gastric banding: 2 (40%) Sleeve gastrectomy: 1 (20% Cholecystectomy: 1 (20%)

Values are mean (range) or n (%).