FIG 2.
The in vivo pathogenicity of Salmonella serovars with low (S. Infantis and S. Lille), moderate (S. Montevideo and S. Oranienburg), and high (S. Typhimurium DT9 and ATCC 14028) in vitro invasiveness was investigated using BALB/c mice. Mice were inoculated with either 103 or 105 CFU. A Kaplan-Meier survival curve illustrates the percent survival rates of mice challenged with nontyphoidal Salmonella isolates. A Mantel-Cox log rank analysis was performed comparing percent survival. Percent survival of mice infected with both S. Typhimurium DT9 (gray dotted line) and ATCC 14028 (black dashed line) was significantly less than that of all other treatment groups (black line) at both 103 (P < 0.001) and 105 (P < 0.0001) CFU. No significant difference in survival rates was observed between S. Typhimurium DT9 and ATCC 14028 for either the low or high dose (n = 7 mice per group).