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. 2014 Dec 10;12:342. doi: 10.1186/s12967-014-0342-7

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© Moogk et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Representative melanoma MMP-23 immunohistochemical scoring. (A) Composite score = 0; (B) Composite score = 3 (intensity = 1, distribution = 2) with faint cytoplasmic immunopositivity; (C) Composite score = 4 (intensity = 2, distribution = 2) with intense cytoplasmic reactivity; (D) Composite score = 5 (intensity = 3, distribution = 2) with very intense cytoplasmic reactivity (400X).