Table 3.
Region | MNI coordinates | Volume | T value | |||
---|---|---|---|---|---|---|
x | y | z | (mm 3 ) | |||
AD > HC | ||||||
Cerebellum | 6 | −64 | −46 | 1,128 | 4.02 | |
Brainstem–midbrain | −4 | −32 | −2 | 272 | 3.40 | |
Precentral cortex | −62 | −12 | 40 | 192 | 3.38 | |
Cuneus | −8 | −96 | 14 | 440 | 3.32 | |
Thalamus | −18 | −24 | 8 | 168 | 3.14 | |
Ventro-lateral prefrontal cortex | 56 | 38 | 10 | 192 | 3.06 | |
HC > AD | ||||||
Posterior cingulate cortex | 10 | −40 | 24 | 456 | 3.69 | |
Superior parietal cortex | 16 | −58 | 72 | 832 | 3.38 | |
Medial prefrontal cortex | 6 | 62 | −4 | 376 | 3.18 | |
Inferior parietal cortex | −36 | −80 | 44 | 1,424 | 3.15 |
All listed clusters significant at p < 0.005 (uncorrected) with a cluster extent threshold of greater than 20 contiguous voxels.
Areas showing a priori hypothesized group differences italicized.
MNI Montreal Neurological Institute, AD anxiety disorder, HC healthy control.