Table 2.

Recurring retroviral integration sites in BCL6 transgenic mice not found in non-transgenic controls.^*

Murine genes containing inserts or, if insert not within a gene, the nearest characterized gene (unless indicated)	Mouse chromosome	Number of mice	Lymphoma type
PIM1 (proviral integration site for Moloney murine leukemia virus 1)	17	7	6T, 1B
GFI1B (growth factor independent 1B)	2	3	B
EVI5 (ecotropic viral integration site 5)	5	3	T
MYB (transcriptional activator MYB isoform 1)	10	3	2B, 1T
LMO2 (LIM domain only 2)	2	2	T
MN1 (probable tumor suppressor protein MN1)	5	2	T
AHI1 (jouberin isoform 1; Abelson helper integration site-1)	10	2	T
BCOR (BCL6 corepressor isoform d)	10	2	B
IKZF1 (DNA-binding protein Ikaros isoform a and b)	11	2	T
SYKb (tyrosine protein kinase SYK)	13	2**	T
MPPE (metallophosphoesterase 1); IMPA2 (inositol monophosphatase 2)	18	2***	B
DNTT (DNA nucleotidylexotransferase)	19	2	T
GATA1 (erythroid transcription factor)	X	2	B

^*Sequences have ≥98% identity to the murine databases described in the text.

^**In one lymphoma, the insert is within SYKb; in the other, SYKb is 61.3 kb 3′ to the insert, but there is a gene closer to the insert at the 5′ side [40.3 kb away, D/RAS2 (GTP-binding protein DI-RAS2)].

^***MPPE (5′) is closer to the insert in one lymphoma (17.8 kb vs. 50.2 kb), but IMPA2 (3′) is closer to the insert in the other lymphoma (1 kb vs. 33.8 kb).