Table 3.
Association between having documented crystal methamphetamine dependence and 1) HIV seroconversion and 2) returning for >1 PEP course
| HIV seroconversion1 | Repeat NPEP Use2 | |||
|---|---|---|---|---|
| HR (95% CI) | aHR (95% CI) | OR (95% CI) | aOR (95% CI) | |
| CM dependence | 2.49 (1.18 to 5.26) | 4.04 (1.71 to 9.53) | 5.87 (3.38 to 10.2) | 5.30 (2.87 to 9.79) |
| Age at first PEP visit | 0.95 (0.91 to 0.99) | 1.01 (0.99 to 1.03) | ||
| In primary care at Fenway Health | 4.00 (0.53 to 30.3) | 2.92 (1.75 to 4.88) | ||
| Any health insurance | 1.20 (0.57 to 2.52) | 1.72 (1.09 to 2.69) | ||
| Race/ethnicity | ||||
| White/Caucasian | Ref | Ref | ||
| Hispanic/Latino | 2.42 (0.98 to 5.99) | 0.97 (0.51 to 1.83) | ||
| African American | 4.40 (1.20 to 16.1) | 1.02 (0.40 to 2.60) | ||
| Asian | NA | 1.43 (0.60 to 3.40) | ||
| Other | NA | 0.99 (0.33 to 2.90) | ||
| History of homelessness | 0.79 (0.57 to 2.52) | 0.53 (0.14 to 1.93) | ||
| History of sex work | 0.85 (0.09 to 7.84) | 0.65 (0.14 to 2.90) | ||
| Depression at time of PEP | 0.89 (0.38 to 2.10) | 1.21 (0.76 to 1.94) | ||
| Anxiety at time of PEP | 1.02 (0.43 to 2.43) | 0.91 (0.56 to 1.48) | ||
| ADHD at time of PEP | 0.54 (0.13 to 2.34) | 1.72 (0.94 to 3.17) | ||
| Bipolar I/II at time of PEP | NA | 1.35 (0.54 to 3.38) | ||
| Year of 1st NPEP Prescription | NA | 0.92 (0.87 to 0.96) | ||
Abbreviations: HR: Hazards Ratio (for Cox models); OR: Odds Ratio (for logistic models); aHR: adjusted Hazards Ratio (for multivariable Cox models); aOR: adjusted Odds Ratio (for multivariable logistic models); CI: confidence interval; Italics indicates statistical significance (P<0.05)
1
Cox proportional hazards model
2
Logistic regression model