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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Immunol. 2014 Nov 17;194(1):325–333. doi: 10.4049/jimmunol.1400497

Figure 6. Genetic deficiency of either PD-L1 or PD-L2 increases kidney dysfunction and injury after mild ischemia-reperfusion injury.

Figure 6

Naïve C57Bl/6 (WT) mice, PD-L1 KO or PD-L2 KO mice were subjected to mild bilateral renal IR injury (21 min ischemia). Plasma creatinine level was assessed after 24 hours of reperfusion (A). ATN scores were determined using H&E stained kidney sections (B). N=5–6 per group, pooled from 3 independent experiments. Data are presented as the mean + SEM, * denotes P<0.05.