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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Immunol. 2014 Nov 17;194(1):325–333. doi: 10.4049/jimmunol.1400497

Table 1.

ATN scores in mice treated with PD-1 ligand blocking antibodies prior to IRI

Sham IRI + Isotype Antibody IRI + anti-PD-L1 IRI + anti-PD-L2 IRI + Both Antibodies
ATN Score 0.2 ± 0.1 0.7 ± 0.3 2.7 ± 0.3** 2.8 ± 0.2** 3.7 ± 0.1**,#

Max ATN Score is 5. Mean ± SEM,

**

denotes P<0.01 vs. IRI + Isotype;

#

denotes P<0.01 vs. IRI + anti-PD-L1 and vs. IRI + anti-PD-L2.

ATN: acute tubular necrosis; PD-1: programmed cell death 1; IRI: ischemia reperfusion injury; PD-L1: PD-1 ligand 1; PD-L2: PD-1 ligand 2.