. Author manuscript; available in PMC: 2016 Jan 1.

Published in final edited form as: J Immunol. 2014 Nov 17;194(1):325–333. doi: 10.4049/jimmunol.1400497

Table 2.

Changes in inflammatory mRNA abundance in the kidney 24 hrs after mild kidney IRI.

	Gene
Group	IL-6	CXCL1	ICAM-1
Sham	1	1	1
IRI + isotype antibody	42 ± 18	21 ± 9	2 ± 1
IRI + anti-PD-L1	342 ± 85	71 ± 28	2.7 ± 0.5
IRI + anti-PD-L2	530 ± 220	89 ± 28	3 ± 0.4
IRI + both antibodies	1,853 ± 565^*	147 ± 36^*	4 ± 1^*

For each mRNA, expression level in sham-operated mice were set to 1 and expression in each treatment group is expressed as relative arbitrary units.

denotes P < 0.05 vs. IRI + isotype antibody group within each column.

IRI: ischemia reperfusion injury; PD-L1: programmed cell death 1(PD-1) ligand 1; PD-L2: PD-1 ligand 2; IL-6: interleukin 6; CXCL1: chemokine (C-X-C motif) ligand 1; ICAM-1: Intercellular Adhesion Molecule 1.