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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Immunol. 2014 Dec 1;194(1):291–306. doi: 10.4049/jimmunol.1401447

FIGURE 7.

FIGURE 7

IgA (A) and IgG (B) secreting plasma cells are a major source of acetylated-p65 (lysine 310) in the colonic lamina propria of chronic-SIV infected rhesus macaques. All panels involve double labels with acetylated-p65 (green) and IgA and IgG (red) for plasma cells. For each panel the individual channels (green for acetylated-p65, and red for IgA or IgG and grey for differential interference contrast (DIC) to reveal tissue architecture appear on the left with a larger merged image on the right. Colocalization of green (acetylated-p65) and red (IgA and IgG) appear light yellow and is indicated by white arrow heads. Note the fewer IgA+ and IgA/acetylated-p65++ plasma cells in the uninfected control macaque (C). Also, notice the paucity of IgG+ and IgG/acetylated-p65++ plasma cells in the uninfected control macaque (D).All panels are shown at 40X magnification.