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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Immunol. 2014 Nov 26;194(1):142–150. doi: 10.4049/jimmunol.1401777

Figure 4. Tryptase and thrombin potentiate fibrocyte differentiation in the presence of human serum.

Figure 4

PBMC were cultured in medium containing serum in the presence of the indicated concentrations of tryptase or thrombin for 5 days, and fibrocytes were counted as in Figure 1. Serum-containing media complete inhibited fibrocyte differentiation in the no-protease control. Values are mean ± SEM, n = 4. * indicates p < .05, ** p < .01, and *** p < .001 compared to the no-protease control (t-test).