Table 2. Comparative toxicity of dcSTX to STX calculated by the median values of the 3 experiments.
Toxins | Toxicity (M.U./µmol) |
Toxicity ratio of dcSTX diacetate salt to STX·2HCl (weight based) |
Toxicity ratio of dcSTX to STX (weight based) |
Toxicity ratio of dcSTX to STX (mole based) |
|
---|---|---|---|---|---|
1st Exp. | STXa) | 1863.0 | - | - | - |
dcSTXb) | 939.0 | 0.498 | 0.589 | 0.504 | |
2nd Exp. | STX | 1924.6 | - | - | - |
dcSTX | 948.5 | 0.487 | 0.576 | 0.493 | |
3rd Exp. | STX | 1981.7 | - | - | - |
dcSTX | 866.5 | 0.433 | 0.511 | 0.437 | |
Ave.± SD | STX | 1,923.1 ± 59.4 | - | - | - |
dcSTX | 918.0 ± 44.9 | 0.473 ± 0.035 | 0.559 ± 0.042 | 0.478 ± 0.036 |
a) The STX standard was provided by the FDA, but more precisely, it was STX·2HCl., b) As dcSTX diacetate salt.